Insuficiencia de vitamina D y riesgo de fractura. (Inglés)

Glowacki, Julie a; LeBoff, Meryl S b

Abstract:

Purpose of review:
Evidence has accumulated to show the prevalence of vitamin D insufficiency and deficiency in all age groups. Inadequate exposure to sunlight and to dietary sources contribute to the reemergence of musculoskeletal problems attributable to hypovitaminosis D.

Recent findings:
There is a growing body of evidence for the alarming prevalence of vitamin D insufficiency and deficiency among healthy adolescents, adults, and elders. Several studies show increased prevalence of vitamin D deficiency among patients with fractures and patients with persistent musculoskeletal pain. Evidence suggests that genetic variations in the vitamin D receptor are associated with fracture risk. There has been a reconsideration of the range of normal laboratory values and recommended daily intake of vitamin D for different groups of individuals. New strategies are needed to identify individuals who would benefit from vitamin D treatments. Identification of vitamin D deficiency in patients with fractures and its correction require the education and cooperation of multiple specialists.

Summary:
Physicians and orthopedic surgeons need to be alert to populations at risk of hypovitaminosis D. Immediate correction and maintenance of vitamin D adequacy require interactions of medical specialists.

Current Opinion in Endocrinology & Diabetes. 11(6):353-358, December 2004.