Cambize Shahrdar MD⁎, Pat Campbell PhD, Joseph Mirra MD and Lawrence D. Dorr MD⁎,
⁎Dorr Arthritis Institute, Department of Orthopedics, Arthritis Institute at Centinela Hospital Medical Center, Inglewood, CA Research Department, Orthopedic Hospital, Los Angeles, CA
Two patients were evaluated for the possibility of hypersensitivity to a Metasul articulation (Centerpulse, Austin, Tex) coupled with total hip arthroplasty. Serum was tested with a lymphocyte proliferation assay, and the capsular tissues from the hip were examined for perivascular lymphocytes. The diagnosis of hypersensitivity to Metasul could not be confirmed in these patients, and ultimately, the painful hip arthroplasties were felt to be caused by a combination of musculoskeletal problems.
The Journal of Arthroplasty Volume 21, Issue 2 , February 2006, Pages 289-293.