«Hipertensión intracraneal como manifestación inical del tumor neuroectodermal espinal.»
Yi-Chun Chena, Lok-Ming Tanga, Chi-Jen Chenb, Shih-Ming Jungc and Sien-Tsong Chena.
aDepartment of Neurology, Chang Gung Memorial Hospital, 199 Tung Hwa North Road, 10591 Taipei, Taiwan bDepartment of Neuroradiology, Chang Gung Memorial Hospital, 199 Tung Hwa North Road, 10591 Taipei, Taiwan cDepartment of Neuropathology, Chang Gung Memorial Hospital, 199 Tung Hwa North Road, 10591 Taipei, Taiwan
A 19-year-old girl had headaches, blurred vision and vomiting for 2 weeks. Neurological examination revealed only bilateral papilloedema and left abducens palsy. Neuroimaging of the brain was normal. Cerebrospinal fluid study showed intracranial hypertension (IH), hypoglycorrhachia, hyperproteinorrhachia, and a negative cytology study. Eight months after the onset, paraparesis occurred. Spinal magnetic resonance imaging showed intramedullary masses at the cervical and thoracic cords with extensive seeding. Biopsy of the mass showed primitive neuroectodermal tumor (PNET). IH rarely occurs in patients with spinal cord neoplasms. Its incidence is low and the condition is always associated with signs of myelopathy. We report a patient whose initial manifestation of spinal PNET was IH only. Spinal tumor should be considered in IH patients whose intracranial examinations are negative.
Clinical Neurology and Neurosurgery Volume 107, Issue 5 , August 2005, Pages 408-411